Kidney transplantation is usually done within blood group compatible people. The donor (who donates the kidney) and the recipient (who receives the kidney) should usually be the same blood group or compatible blood group. If blood group is incompatible transfusion is done, it results in serious reactions. Likewise blood group incompatible kidney transplantation (across the blood group) results in the rejection of the transplanted kidney. In the past, blood group incompatible transplantation was not performed. But now path-breaking research is opening up new possibilities.
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