At MIOT International, managing complex neurological cancers requires more than advanced technology alone. It demands precise diagnosis, multidisciplinary expertise, and a coordinated treatment strategy focused on both disease control and functional recovery.

This case highlights how a comprehensive approach involving Radiation Oncology, Neuro-oncology, Diagnostic Imaging, and Neurorehabilitation helped restore mobility and independence for a patient diagnosed with a rare and diffuse spinal cord tumour.

A Challenging Clinical Presentation

A 48-year-old patient from Fiji presented with rapidly worsening neurological symptoms that had progressively affected his mobility and quality of life.

  • Rapidly progressive weakness in both lower limbs
  • Sensory loss affecting mobility and daily activities
  • Bladder dysfunction
  • Progressive neurological deterioration despite previous treatment

Prior interventions, including chemoradiation, had failed to halt symptom progression, prompting further evaluation at MIOT International.

Uncovering a Rare Diagnosis

The multidisciplinary team at MIOT International conducted a comprehensive neurological assessment using advanced imaging and diagnostic investigations. Detailed evaluation, including MRI and cerebrospinal fluid analysis, revealed tumour involvement of the protective membranes surrounding the spinal cord.

Further pathological examination confirmed the diagnosis of:

 

Diffuse Leptomeningeal Glioneuronal Tumour (DLGNT)

DLGNT is a rare tumour of the central nervous system characterised by diffuse spread along the coverings of the brain and spinal cord. Due to its uncommon presentation and extensive involvement, diagnosis and treatment often require specialised expertise and advanced imaging capabilities.

Advanced Radiation Therapy Across the Entire Spine

Following detailed multidisciplinary review, the team formulated a highly individualised treatment plan.

Given the diffuse involvement of the spinal coverings, the patient underwent treatment using advanced Volumetric Modulated Arc Therapy (VMAT).

  • Highly precise radiation delivery across the entire spine
  • Uniform dose distribution throughout the treatment area
  • Protection of surrounding healthy tissues and organs
  • Preservation of spinal cord function
  • Reduced treatment-related side effects

The treatment was delivered using advanced planning systems and image-guided radiotherapy protocols to ensure exceptional precision throughout the course of treatment.

MIOT’s Multidisciplinary Expertise

The patient’s case was reviewed by MIOT’s multidisciplinary tumour board, bringing together specialists from Radiation Oncology, Neuro-oncology, Neurosurgery, Radiology, Pathology, and Rehabilitation Medicine.

This collaborative approach enabled the team to develop a highly personalised treatment strategy focused on disease control while preserving neurological function and quality of life.

  • Over three decades of clinical excellence
  • Comprehensive multidisciplinary tumour board review
  • Advanced diagnostic capabilities for complex and rare conditions
  • Expertise in performing biopsies in anatomically challenging locations
  • Precision radiation therapy with sub-millimetre accuracy
  • Advanced imaging and treatment planning systems

The Road to Recovery Through Neurorehabilitation

Following radiation therapy, the patient underwent six weeks of intensive neurorehabilitation at MIOT International.

The rehabilitation programme focused on:

  • Improving lower limb muscle strength
  • Restoring gait stability and mobility
  • Enhancing posture and balance control
  • Improving overall functional independence

Through a structured and personalised rehabilitation programme, the patient progressively regained mobility, independence, and confidence.

Clinical Outcome

The integrated treatment and rehabilitation approach resulted in significant clinical improvement.

  • Improved lower limb strength
  • Restoration of mobility and walking ability
  • Better balance and postural control
  • Improved functional independence
  • Enhanced overall quality of life

The case demonstrates how coordinated cancer care and rehabilitation can help patients recover meaningful function even in the face of rare and complex neurological conditions.

Advanced Cancer Care at MIOT International

For more than three decades, MIOT International has been delivering comprehensive cancer care supported by advanced technology and multidisciplinary expertise.

 

  • Advanced diagnostic imaging
  • Precision radiation therapy
  • Multidisciplinary tumour board evaluation
  • Expertise in managing rare and complex tumours
  • Comprehensive neurorehabilitation services
  • Personalised treatment planning

By combining innovation, collaboration, and patient-centred care, MIOT continues to deliver successful outcomes for patients facing challenging oncological and neurological disorders.

To know more about MIOT Institute of Cancer Cure, visit: https://www.miotinternational.com/centers-of-excellence/miot-institute-of-cancer-cure/ 

To know more about MIOT Rehab Centre, visit: https://miotrehabcentre.com/